Housing and respiratory health: Exposures, health effects and interventions

Housing quality and affordability are well established as social determinants of health through direct and indirect mechanisms. Respiratory illnesses related to housing are nearly all the result of housing disrepair that allows intrusion into the home of environmental agents that are directly or indirectly associated with disease. Structural deficiencies such as leaks, cracks in the foundation or holes in the home's exterior can facilitate the presence of mould, which is causally linked to the development of asthma and is associated with exacerbation of asthma symptoms in children and adults. Indoor cleanliness can also contribute to the presence of mice and cockroaches. Proper ventilation can improve air quality, reducing exposure to PM, VOCs and infectious respiratory agents. Disparities in exposure to the housing conditions associated with respiratory disease are readily apparent across socioeconomic lines. Low-income families are less likely to be able to afford the costs of maintaining a home, which prevents them from making repairs that could improve respiratory health.Copyright © ERS 2023.

PLANT TESTING MAGNETIC CONDITIONING ON KENNECOTT'S Cu-Mo PORPHYRY ORE

Over it's more than 100-year history, the Kennecott operation has often been at the forefront of innovation;driven by the demands of the lower grade ore-body and the higher costs of operating in the US where wages are generally higher and regulation more restrictive. One way of reducing operating costs in c/lb is to increase the lbs produced at minimal cost. Despite the relatively coarse grind at Kennecott - about 30% >150μm, approximately 20% of the Cu lost to tail is liberated chalcopyrite in the <20μm fraction, and about 30%-40% in the <37μm fraction. In 2020 Kennecott undertook a detailed plant scale test of the magnetic aggregation technology to increase copper recovery by reducing fine copper losses. A paired statistical plant test of magnetic conditioning on one rougher line showed a 1.12% increase in Cu recovery to 97% statistical confidence. The next challenge, unforeseen at the start of the project, was the fabrication and transportation to site of the equipment for the three remaining rougher rows, during the severe supply-chain constraints of the Covid pandemic in 2021. This resulted in delays and unforeseen costs as world-wide transportation became chaotic, particularly transportation via west coast USA. Nevertheless, the project was completed and commissioned, with only minor delays and cost increases, due to a flexible approach to overcoming the hurdles encountered. Copyright © 2023 by SME.

The Study of 'Preparation Guidelines' Towards Phetchabun Government Officers and Health Massage Establishments

The purpose of research was to study practices, barriers, and solutions of Phetchabun health massage establishments under COVID-19 situation. Non-participant observation, informal interview, in-depth interview, and participation observation were carried out respectively. Purposive sampling was used with 15 health consumer protection officers in charge;11 district level, 2 provincial level, 2 regional level as well as each representative of 11 districts. Results after implementation of "Preparation Guidelines for Health Spa, Health Massage, and Beauty Massage to Promote Health Tourism During COVID-19 Pandemic" were categorized into two sections. Firstly, the practices, barriers, and solutions of government officer performances included preparation for reopening, monitoring of the provider practices, and performance report. Secondly, the provider operations consisted of doing "Self-Assessment of Health Establishment", logging-in webpage before reopening, and practices for clients included screening and report of patients under investigation, establishment monitor, service, and establishment cleaning. In summary, the preparation guidelines were purposed to reopen their business with numerous contents and messages written by official language, it caused establishment providers and practitioners difficultly understood when applying. LINE Application and making calls were easy and accessible methods for their communication to reach current data and to ensure exact information. Various encouragements and having compliments were also considerable to form trust and confidence among them, they also raised their proud.Copyright © 2023, World Informations Syndicate. All rights reserved.

Preface

The title of the ConferenceXXII Conference of PhD Students and Young Scientists "Interdisciplinary topics in mining and geology”The location and the date of the conferencevirtual event – online conference, June 29th to July 1st, 2022 in Wrocław, PolandXXIInd Conference of PhD Students and Young Scientists "Interdisciplinary topics in mining and geology” continues a series of events that started in 2000 at Wrocław University of Science and Technology. Scientific programme of the Conference focuses on four thematic panels:1. Mining Engineering: sustainable development, digitalisation in mining, problems of securing, protecting and using remnants of old mining works, underground mining, opencast mining, mineral processing, waste management, mining machinery, mine transport, economics in mining, mining aeronautics, ventilation and air conditioning in mines,2. Earth and Space Sciences: geology, hydrogeology, environmental protection, extraterrestrial resources, groundwater and medicinal waters, engineering and environmental protection, geotourism,3. Geoengineering: environmental protection, applied geotechnics, rock and soil mechanics, geohazards,4. Geoinformation: mining geodesy, GIS, photogrammetry and remote sensing, geodata modeling and analysis.The XXII Conference of PhD Students and Young Scientists was held as a virtual event, that is as a virtual, online conference in real-time. The reason why the Organizing Committee decided to change the traditional formula of the event to online formula was related to the concern for the health of the participants due to the COVID-19 epidemic.The XXII Conference of PhD Students and Young Scientists took place from June 29th to July 1st, 2022 in Wroclaw, Poland. That is the organizers worked and managed the event from the Wrocław University of Science and Technology Geocentre building. Because the conference focused on four thematic panels, four different special opening lectures were delivered by wellknown scientists- Professor Jan Zalasiewicz (University of Leicester, England)- Associate Professor Artur Krawczyk (AGH University of Science and Technology, Poland)- Professor Biljana Kovacević-Zelić (University of Zagreb, Croatia)- Assistant Professor Eduard Kan (Tashkent Institute of Irrigation and Agricultural Mechanizations Engineers, Uzbekistan).The Conference was divided into 8 oral sessions (with 33 presentations) and 1 poster session (with 33 posters). The amount of time provided to one presentation was 15 minutes, after presentation there was 5 minutes available for discussion. The poster session was available throughout the event, and the posters were available for online viewing on the Conference's website with the possibility of make discussion and ask questions in real time via zoom meeting application as well. Every day of the Conference one "virtual coffee break” was devoted for discussion between participants and question and answer session for the Organizers.There were 96 registered participants from 13 countries. The online XXII Conference of PhD Students and Young Scientists was conducted using the Zoom meeting platform with commemorative screen shots taken. By tradition two competitions, for the best oral presentation and for the best poster were held. The award for the best oral presentation was given ex aequo to Julia Tiganj (TH Georg Agricola University of Applied Sciences, Germany) for the presentation entitled Post-mining goes international: hurdles to climate neutrality using the example of China and Oksana Khomiak, Jörg Benndorf (TU Bergakademie Freiberg, Germany) for the presentation entitled Spectral analysis of ore hyperspectral images at different stages of the mining value chain, whereas the best poster was awarded to Adam Wróblewski, Jacek Wodecki, Paweł Trybała, Radosław Zimroz (Wrocław University of Science and technology, Poland) for the poster entitled Large underground structures geometry evaluation based on point cloud data analysis.List of Scientific Committee, Organizing Committee, Editorial Team are available i this pdf.

Research progress on influence of environmental and meteorological parameters on transmission of coronavirus disease 2019

Novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-COV-2) is spreading rapidly around the world and has become a global pandemic. Meteorological factors have been recognized as one of the critical factors that influence the epidemiology and transmission of infectious diseases. In this context, the World Meteorological Organization and scholars at home and abroad have paid extensive attention to the relationships of environment and meteorology with COVID-19. This paper systematically collected and sorted out relevant domestic and foreign studies, and reviewed the latest research progress on the impact of environmental and meteorological factors on COVID-19, classifying them into typical meteorological factors (such as temperature, humidity, and wind speed), local environmental factors (such as indoor enclosed environment, ventilation, disinfection, and air conditioning), and air pollution. Current research evidence suggests that typical meteorological factors, local environmental factors, and air pollutants are closely related to the transmission of COVID-19. However, the results of different studies are still divergent due to uncertainty about the influencing mechanism, and differences in research areas and methods. This review elucidated the importance of environmental and meteorological factors to the spread of COVID-19, and provided useful implications for the control of further large-scale transmission of COVID-19 and the development of prevention and control strategies under different environmental and meteorological conditions.Copyright © 2022, Shanghai Municipal Center for Disease Control and Prevention. All rights reserved.

Fault detection model for a variable speed heat pump

The impact of the COVID pandemic has resulted in many people cultivating a remote working culture and increasing building energy use. A reduction in the energy use of heating, ventilation, and air-conditioning (HVAC) systems is necessary for decreasing the energy use in buildings. The refrigerant charge of a heat pump greatly affects its energy use. However, refrigerant leakage causes a significant increase in the energy use of HVAC systems. The development of refrigerant charge fault detection models is, therefore, important to prevent unwarranted energy consumption and CO2 emissions in heat pumps. This paper examines refrigerant charge faults and their effect on a variable speed heat pump and the most accurate method between a multiple linear regression and multilayer perceptron model to use in detecting the refrigerant charge fault using the discharge temperature of the compressor, outdoor entering water temperature and compressor speed as inputs, and refrigerant charge as the output. The COP of the heat pump decreased when it was not operating at the optimum refrigerant charge, while an increase in compressor speed compensated for the degradation in the capacity during refrigerant leakage. Furthermore, the multilayer perception was found to have a higher prediction accuracy of the refrigerant charge fault with a mean square error of ± 3.7%, while the multiple linear regression model had a mean square error of ± 4.5%. The study also found that the multilayer perception model requires 7 neurons in the hidden layer to make viable predictions on any subsequent test sets fed into it under similar experimental conditions and parameters of the heat pump used in this study.

Estimating SARS-CoV-2 infection risk in university dormitories using CO2 pulse injections

Air movement dynamics within three student dormitories were studied with simulated carbon dioxide (CO2) pulse injections to understand SARS-CoV-2 transmission risk. CO2 decay rate, proportion of shared air, and transport time were calculated from dynamic CO2 measurement data within simulated source and adjacent receptor rooms. Applying a Wells-Riley infection risk analysis with these results, the risk of SARS-CoV-2 infection in adjacent rooms ranged from 1% to 58% assuming an average emission rate of 5 quanta per hour and exposure duration of 3.5 days. Door opening status was very influential in resulting risk and vertical transport from source to above rooms was observed in all dormitories. © 2022 17th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2022. All rights reserved.

Development of an automatic window opening system to control the ventilation rate

Under the influence of COVID-19, it is recommended to ventilate to reduce the risk of infection in the room. In an air-conditioned room, window open can increased the ventilation rate that caused by indoor and outdoor temperature difference. However, there is a concern that opening window in the air-conditioned room will increase the heating and cooling load due to air leakage. In addition, it is difficult to maintain the appropriate ventilation rate because the outdoor air temperature changes time to time. To solve this problem, we have developed an automatic window opening system to control the natural ventilation rate. In this study, actual measurements were conducted to understand the operating performance of the system, and its effect on the indoor thermal environment. As a result, it was confirmed that the ventilation rate could be controlled by this system. © 2022 17th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2022. All rights reserved.

Severe Acute Hepatitis: An Emerging Grave Illness in Children

Acute hepatitis of unknown origin in children has been recently described in the literature, and a case definition has also been proposed for this condition. The exact etiology is unknown and exclusion of infectious, metabolic, autoimmune and toxin mediated injuries is essential. Management for this condition is supportive, but some may require liver transplantation. Infection prevention and control practices are important as the etiology remains unidentified.Copyright © 2023, Indian Academy of Pediatrics.

SURVEY ON VENTILATION, INDOOR ENVIRONMENT, AND MEASUREMENT AGAINST COVID-19 IN CLUBS AND BARS (PART 1): OVERVIEW OF BUILDING FACILITIES, VENTILATION CONDITION AND INFECTION STATUS

From the early stages of the COVID-19 outbreak, there have been many reports on cluster infections in clubs and bars. Meanwhile, there is no report on the indoor air environment in those places and it will limit measures for infection control. This study aims to understand the indoor air and ventilation environment and to propose practical and appropriate improvement measures for related industries. In addition to measuring CO2 concentration in clubs and bars in Tokyo, we have surveyed the voluntary measures taken against COVID-19, outlines of building and ventilation/air conditioning equipment, ventilation regime, and so on. © 2023 Architectural Institute of Japan. All rights reserved.

Successful matched unrelated donor hematopoietic stem cell transplantation for infantile Wolman disease

Introduction: Wolman disease is a rare genetic disorder with an autosomal recessive inheritance. A mutation in the LIPA gene causes lysosomal acid lipase (LAL) deficiency results in lipid storage and adrenal insufficiency. Death in early infancy is due to liver failure. Patients and methods: We describe the clinical course of a three-month-old infant diagnosed with Wolman disease. A rapid mutational analysis confirmed a LIPA gene defect. Results: He underwent matched unrelated donor peripheral blood stem cell hematopoietic stem cell transplantation (HSCT) at 3 months of age, with a treosulfan-based conditioning, which resulted in engraftment with donor-derived hematopoietic cells. He required supportive care for sinusoidal obstruction syndrome and mucositis. He was administered low dose prednisolone for grade I skin graft versus host disease, and a complete donor chimerism was documented on several occasions. At one year post HSCT, his growth and development were optimal, and there was no hepatosplenomegaly. He is maintained on glucocorticoid and mineralocorticoid supplements for primary hypoaldosteronism. Conclusion: The case emphasizes the timely diagnosis and the potential for successful treatment of Wolman disease by HSCT. © 2022 Pediatric Hematology Oncology Chapter of Indian Academy of Pediatrics

Post-Transplantation Cyclophosphamide for the Prevention of Graft-Versus-Host Disease Should Not Limit Transplantation for Acute Lymphoblastic Leukemia in People with Trisomy 21

Introduction: Use of hematopoietic cell transplantation (HCT) in patients with trisomy 21 (+21) is infrequent given concerns about increased toxicity with cytotoxic chemotherapy.1 Due to increasing evidence of benefit from post-HCT cyclophosphamide (PTCy) for graft-vs.-host disease (GVHD) prophylaxis and lack of prior descriptions in patients with +21,2-4 we report on 2 patients with +21 and acute lymphoblastic leukemia (ALL) who underwent HCT with PTCy. Method(s): Retrospective data were collected from 2 patients with ALL and +21 who underwent allogeneic HCT with PTCybased GVHD prophylaxis from 2019 to 2021. Data collected included age, disease risk, HCT-CI, GVHD incidence, and survival. Result(s): Patient 1 is a 22-year-old male and patient 2 a 25-year-old female. Both had Ph-negative, B-cell ALL. Patient 1 had ETV6/RUNX1 rearrangement, del 12p, gain of X, and he had recurrence of measurable residual disease (MRD) after initial MRD-negative CR with two lines of therapy pre-HCT. Patient 2 had normal cytogenetics and relapsed disease with 4 prior lines of therapy. Both achieved MRD-negativity pre-HCT. Both received fludarabine and melphalan conditioning, and patient 1 also received thiotepa 2.5 mg/kg. PTCy was given on days +3 and 4 at 50 mg/kg with sirolimus and tacrolimus for GVHD prophylaxis. Patient 1 had a haploidentical donor and received one dose of rabbit ATG (1 mg/kg) on day +5. Patient 2 had a matched unrelated donor. There was no significant delay in engraftment of ANC (day 16-19) or platelets (day 15-16). Patient 2 developed acute GVHD at day 30 (stage I skin, stage II GI) that resolved with steroids which were tapered off by day 96 without recurrence. Sirolimus stopped at day 79 (pt 1) and 103 (pt 2) and tacrolimus was stopped at day 274 (pt 1) and 469 (pt 2). Patient 1 developed a sirolimus-induced pericardial effusion at day 84 which did not recur after sirolimus discontinuation. Patient 2 developed moyamoya 8 months post-HCT during tacrolimus taper without other GVHD symptoms. Response to steroids was noted, so tacrolimus was restarted for residual neurological deficit. Neither patient developed chronic GVHD or left ventricular ejection fraction decline, and neither patient had disease relapse at follow-up of 30 and 16 months respectively. Patient 2 developed COVID pneumonia 16 months post-HCT and died while in CR. Patient 1 remains alive, in CR, and off immunosuppression nearly 3 years post HCT. Conclusion(s): Allogeneic HCT with PTCy at standard doses did not appear prohibitively toxic in patients with +21 when administered after reduced-intensity conditioning. In this case series, GVHD rates seemed consistent with larger series in patients without +21. Moyamoya development is associated with autoimmunity in patients with +21 and hence may have been GVHD-related5. Trisomy 21 should not be a barrier to patients otherwise eligible for HCT, even with PTCy prophylaxis.Copyright © 2023 American Society for Transplantation and Cellular Therapy

Outcomes of Cryopreserved Vs Fresh Haploidentical Allogeneic Donor Grafts Using Post-Transplant Cyclophosphamide (PTCy) for Gvhd Prophylaxis

The World Health Organization (WHO) declared COVID-19 a pandemic in March 2020. Since then, logistical challenges arose regarding the procurement of allogeneic (allo) hematopoietic stem cell (HSC) donor grafts. Little data was available on transplant outcomes using cryo haploidentical (haplo) HSC grafts with post-transplant cyclophosphamide (PTCy) for GVHD prophylaxis. We retrospectively analyzed patients who received a first PTCy-based haplo hematopoietic stem cell transplant (Haplo HCT) at a single outpatient transplant center between January 2015 and December 2021. We identified 294 patients, 179 received a fresh graft and 115 received a cryo graft (Table 1). Both cohorts were similar in terms of median age, diagnoses, HCT-CI score and DRI. Out of 179 fresh haplo grafts, 160 (89.4%) were from peripheral blood stem cells (PBSC) and 19 (10.6%) were bone marrow grafts (BM). There were no cryo BM grafts used. Conditioning intensity were similar amongst both cohorts, with 43% myeloablative, 41.9% non-myeloablative and 15.1% RIC regimens used for fresh Haplo HCT and 39.1% myeloablative, 42.6% non-myeloablative and 18.3% RIC cryo Haplo HCT. Median time to engraftment was 16 days for fresh Haplo HCT and 17 days for cryo HCT (p=0.18). Median time to platelet engraftment was 27 days for fresh Haplo HCT and 27.5 days for cryo HCT (p=0.96). Since March 2020, only 8 transplants performed at our institution were from fresh haplo HSC grafts. Cryo grafts performed after March 2020 accounted for 73 (63.5%) of 115 total cryo Haplo HCT performed in the period reviewed. Using a Cox model to evaluate the effect of graft type and adjusting for significant variables, we found no difference in overall survival (OS), disease free survival (DFS), non-relapse mortality (NRM) and relapse rates between fresh and cryo Haplo HCT performed (Figure 1). While we found no difference in grades III-IV aGVHD (Table Presented) (Figure Presented) between fresh vs cryo Haplo HCT, we found a statistically significant higher incidence of grades II-IV aGVHD (p=0.033). There was no difference in all-grade cGVHD (p=0.53) or moderate- severe cGVHD (p=0.86) (Figure 2).(Figure Presented) The National Marrow Donor Program (NMDP) released a statement requiring cryopreservation of unrelated donor grafts at the start of the COVID-19 pandemic. The cryopreservation of all types of allo HSC grafts has been adopted by many transplant programs including ours. Our results mimic a CIBMTR analysis published at the start of the pandemic, where survival outcomes using fresh vs cryo haplo HSC grafts with PTCy as GVHD prophylaxis were similar. Contrary to other reports, we did not see differences in graft failure or rates of cGVHD between fresh and cryo Haplo HCT. The use of cryopreserved HSC grafts for Haplo HCT with PTCy results in favorable outcomes in an outpatient transplant setting. Further studies are needed to determine the cost-effectiveness of this practice in the post-pandemic era.Copyright © 2023 American Society for Transplantation and Cellular Therapy

Implementation of Blockchain Technology Could Increase Equity and Transparency in Organ Transplantation: A Narrative Review of an Emergent Tool.

In the last few years, innovative technology and health care digitalization played a major role in all medical fields and a great effort worldwide to manage this large amount of data, in terms of security and digital privacy has been made by different national health systems. Blockchain technology, a peer-to-peer distributed database without centralized authority, initially applied to Bitcoin protocol, soon gained popularity, thanks to its distributed immutable nature in several non-medical fields. Therefore, the aim of the present review (PROSPERO N° CRD42022316661) is to establish a putative future role of blockchain and distribution ledger technology (DLT) in the organ transplantation field and its role to overcome inequalities. Preoperative assessment of the deceased donor, supranational crossover programs with the international waitlist databases, and reduction of black-market donations and counterfeit drugs are some of the possible applications of DLT, thanks to its distributed, efficient, secure, trackable, and immutable nature to reduce inequalities and discrimination.

Air filtration mitigates aerosol levels both during and after endoscopy procedures.

Objectives: Upper gastrointestinal endoscopies are aerosol-generating procedures, increasing the risk of spreading airborne pathogens. We aim to quantify the mitigation of airborne particles via improved ventilation, specifically laminar flow theatres and portable high-efficiency particulate air (HEPA) filters, during and after upper gastrointestinal endoscopies. Methods: This observational study included patients undergoing routine upper gastrointestinal endoscopy in a standard endoscopy room with 15-17 air changes per hour, a standard endoscopy room with a portable HEPA filtration unit, and a laminar flow theatre with 300 air changes per hour. A particle counter (diameter range 0.3 µm-25 µm) took measurements 10 cm from the mouth. Three analyses were performed: whole procedure particle counts, event-based counts, and air clearance estimation using post-procedure counts. Results: Compared to a standard endoscopy room, for whole procedures we observe a 28.5x reduction in particle counts in laminar flow (p < 0.001) but no significant effect of HEPA filtration (p = 0.50). For event analysis, we observe for lateral flow theatres reduction in particles >5 µm for oral extubation (12.2x, p < 0.01), reduction in particles <5 µm for coughing/gagging (6.9x, p < 0.05), and reduction for all sizes in anesthetic throat spray (8.4x, p < 0.01) but no significant effect of HEPA filtration. However, we find that in the fallow period between procedures HEPA filtration reduces particle clearance times by 40%. Conclusions: Laminar flow theatres are highly effective at dispersing aerosols immediately after production and should be considered for high-risk cases where patients are actively infectious or the supply of personal protective equipment is limited. Portable HEPA filers can safely reduce the fallow time between procedures by 40%.

Evaluation of ventilation in Australian school classrooms using long-term indoor CO2 concentration measurements

School classrooms are often reported as having insufficient ventilation with elevated indoor CO2 concentrations. This paper reports on pre-pandemic field measurements of CO2 concentration levels conducted for an academic year in 10 classrooms from four primary and a secondary school in Victoria, Australia. Measured CO2 concentrations across the 10 classrooms which were operated with a mix of intermittent natural ventilation and air-conditioning for cooling or heating, on average ranged between 657 ppm and 2235 ppm during school hours with median over 1000 ppm in 70% of classrooms. All 10 classrooms in the study exceeded the Australian recommended limit of 850 ppm. Using average peak CO2 concentrations from year-long measurements, estimated ventilation rate (VR) of 4.08 Ls-1 per person show under-performing classrooms where 60% had VRs 35–40% lower than the 10-12 Ls−1 per person Australian recommendation. Estimated VR range of 1.24–2.07 Ls-1 per person using peak maximum CO2 levels were 19–30% lower than ASHRAE recommendation of 6.7 Ls-1 per person. These VRs translate to a range of air change rates on average between 0.52 and 0.88 h−1 ± 0.26–0.59, well below the 6.0 h−1 recommendation for good indoor ventilation by the World Health Organisation in the context of COVID-19 pandemic. Characterisation of ventilation and indoor air quality in current Australian classroom stock is critical for the improvement of classroom design, induction on room operating practices, understanding of the school community on the relevance of building ventilation on school performance and health, and development of appropriate ventilation and indoor air quality guidelines for schools. © 2023 The Authors

The Need for a Paradigm Shift toward an Occupant-Centered Environmental Control Model

Office-based environmental control systems are centralized and designed to control entire spaces, ignoring use dynamics and requirements, and despite being regulated by standardized comfort models, they fail to satisfy real occupants, mainly due to their varied individual characteristics. This research is field-based with a quantitative approach and correlational design. Its objective is to empirically demonstrate that open-plan design, where different users share the same space and generalized environmental conditions, lacks a holistic view of IEQ criteria and the integration of other factors that affect health and well-being. Four buildings are chosen in different Chilean cities, measuring temperatures and CO2 levels at different desks, and applying a survey, which was designed as part of the research to analyze the estimation of relationships between variables and to reveal the factors that cause differences among occupants. The results show that people's satisfaction is multivariable and depends on other factors that positively or negatively stimulate their sensations and perceptions, such as, for example, the option to personally control their environmental conditions. Likewise, it is evident that to achieve comfort, health is being affected while in the building.

Thermal Performance Assessment of Envelope Retrofits for Existing School Buildings in a Hot–Humid Climate: A Case Study in Chennai, India

This study aims to propose building envelope retrofit packages for existing naturally ventilated school buildings in the hot–humid climatic region of Chennai, India. Indoor thermal parameters were collected through field studies from nine sample classrooms of a selected school building in May 2019, between 9.00 am and 4.00 pm. The thermal performance assessment of the existing building was performed by examining the discomfort hours using the CBE thermal comfort tool. Envelope retrofit strategies gathered from the literature and building standards were applied and studied through simulation. The findings reveal the enormous potential to increase the thermal comfort of existing school buildings through envelope retrofit measures. The results demonstrate that the whole-building temperature can be reduced up to 3.2 °C in summer and up to 3.4 °C in winter. Implementing retrofit measures to the building envelopes of existing buildings will help school owners to increase the comfortable hours of whole buildings by up to 17%. In comparison, annual energy savings of up to 13% for the whole building can be made by enhancing the thermal performance of the building envelope. The findings will also help architects to optimise thermal performance and energy usage with minimal interventions.

Ensayo clínico aleatorizado en pacientes COVID- 19 sobre el efecto de la fisioterapia precoz en su acondicionamiento físico

Introduction: The WHO recommends early rehabilitation and mobilization interventions in patients hospitalized for COVID-19. The benefits of early physiotherapy, during the hospital stay, have not been proven in clinical trials. Objective: To evaluate the effects of early physiotherapy and health education in hospitalized COVID-19 patients, in relation to the symptoms described in previous studies, analyzing differences between groups regarding their physical conditioning, need for oxygen therapy and hospital stay. Methodology: Randomized clinical trial with two arms, developed in hospitalization and intermediate respiratory care units, with COVID-19 patients. Sixty-four patients included in the experimental group (implementation of an early physiotherapy program after 48–72 h of admission) and 62 patients in the control group (usual treatment of the center). Sociodemographic and clinical variables: mMRC, oxygen therapy, MRC-SS, 30 s-STST, FPM, Tinetti, FRAIL Scale and PCFS. They were evaluated on admission, discharge and two months after discharge. Results: The experimental patients had fewer days of admission and conventional oxygen therapy. At discharge, they present a lower risk of falling (72.9% vs. 95.8%) and less weakness in MRC-SS (2.1% vs. 14.6%). At two months they had less frailty (5.0% vs. 14.5%), greater hand grip strength, less dyspnea, better results in 30s-STST and fewer post-COVID limitations (86.5% vs. 96.4%). Conclusión: The intervention of early physiotherapy in COVID-19 patients and the health education received, prevents muscle weakness during admission, improves physical conditioning at discharge and two months later, and reduces the days of hospital stay. ClinicalTrials.gov (NCT05032885). © 2023 Asociación Española de Fisioterapeutas

The Effect of the Covid-19 Pandemic on Education Costs in Vocational Nutrition Polytechnic

Vocational education plays a strategic role in the creation of a skilled workforce who is ready to enter the world of work. In order to achieve the standard competency level, the proportion of practice is required to be 60% and large financing is required. During the Covid-19 pandemic there were many changes in the world of education, PBM had to be done online or online, children's education costs were not fulfilled due to layoffs, the economy slumped and had an impact on entrepreneurship and the influence of student personal costs. The cost of education has changed a lot. A study of changes in financing is needed for planning learning in covid conditions and demands for changes in learning patterns in the 4.0 era. The design used in this research is an explanatory mixed method research, quantitative data is taken together with qualitative data collection. The independent variable is the influence of the pandemic, the dependent variable is the cost of education (education budget and student personal costs). Online survey using googleform. The sample of level II and III students who have been exposed to face-to-face and online learning is 143 students. The education budget & costs are presented with the percentage of reduction and increase. Individual operational costs before and during the pandemic were used the Mann Whitney test at 95% confidence level. The recurrent cost budget that is used to finance the operational activities of PBM for D3 Nutrition Study Program for one budget year, with the predicate BLU should have financial management flexibility, so that student advice to provide tuition fee relief, complete facilities (campus wifi, practical equipment, air conditioning class), providing adequate quotas and spending for practical purposes as well as sufficient costs for student activities can be facilitated. All budget items decreased during the epidemic, except for the cost of providing goods and services for competency and IT compliance. The results of the survey on individual personal costs showed that the significance of all items in question, parents' income, living costs and transport costs decreased before and during the pandemic, while Quota and refreshing costs / personal needs increased on average. A deeper study is needed on the education budget and changes in individual operational costs during the Covid-19 pandemic and facing the challenges ahead in the 4.0 era.Copyright © 2020 Ubiquity Press. All rights reserved.